Effects of the hallucinogen psilocybin on habituation and prepulse inhibition of the startle reflex in humans

Abstract

Schizophrenic patients exhibit deficits in indices of sensorimotor gating, such as habituation and prepulse inhibition (PPI) of the startle reflex. Hallucinogenic drug-induced states are putative models for the early and acute stages of schizophrenic and schizophrenia-spectrum …