Effects of ibogaine and noribogaine on the antinociceptive action of μ-, δ-and κ-opioid receptor agonists in mice

Abstract

Ibogaine, an alkaloid isolated from the bark of the African shrub, Tabernanthe iboga, has been claimed to decrease the self-administration of drugs of abuse like morphine, cocaine and alcohol. To determine whether these effects are mediated via opioid receptor systems …