Effect of ibogaine on naloxone-precipitated withdrawal syndrome in chronic morphine-dependent rats.

ED Dzoljic, CD Kaplan, MR Dzoljic - Archives internationales de …, 1988 - ncbi.nlm.nih.gov

Abstract

Ibogaine, an indole alkaloid, administered intracerebroventricularly 4-16 micrograms, attenuated a naloxone-precipitated withdrawal syndrome in chronic morphine-dependent rats. It appears that ibogaine has a more consistent effect on certain selective withdrawal …

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