Blockade of neuronal tryptamine receptors by metoclopramide

Abstract

Abstract Metoclopramide (0.13, 0.51, 2.0 and 8.1× 10− 6 M) caused parallel, rightward, shifts in the dose response curves to 5-HT on the isolated rabbit heart. A sinificant straight line relationship was found between log (5-HT dr− 1) and log [metoclopramide](molar) with a …