Autoregulation of glial cell line‐derived neurotrophic factor expression: implications for the long‐lasting actions of the anti‐addiction drug, Ibogaine

Abstract

We recently showed that the up‐regulation of the glial cell line‐derived neurotrophic factor (GDNF) pathway in the midbrain, is the molecular mechanism by which the putative anti‐addiction drug Ibogaine mediates its desirable action of reducing alcohol consumption (1) …