Ketamine and Postoperative Depressive Symptom-PASSION
Brief Summary
Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay. This study aims to determine whether ketamine could improve the depressive symptom of peirioperative patients. It will also examine the safety for administrating ketamine as an antidepressant intraoperatively. Meanwhile, it will show if ketamine could improve anxiety, postoperative pain or delirium. This trial also will bring great concerns on patients with perioperative mental health and explore the measures to improve their psycho-related prognosis.
Condition or Disease
- Ketamine; Depressive Symptom; Neurosurgery; Perioperative Period
Phase
Study Design
| Study type: | Interventional |
|---|---|
| Status: | Completed |
| Study results: | No Results Available |
| Age: | 18 Years to 65 Years (Adult, Older Adult) |
| Enrollment: | 84 () |
| Funded by: | Other |
Masking |
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Clinical Trial Dates
| Start date: | Jul 05, 2017 | |
|---|---|---|
| Primary Completion: | Aug 24, 2018 | |
| Completion Date: | Nov 20, 2018 | |
| Study First Posted: | Mar 22, 2017 | |
| Results First Posted: | Aug 31, 2020 | |
| Last Updated: | Jul 07, 2020 |
Sponsors / Collaborators
Lead Sponsor:
N/A
Responsible Party:
N/A
Location
Eligibility Criteria
| Sex: | All |
|---|---|
| Minimum Age: | 18 |
| Maximum Age: | 65 |
More Details
| NCT Number: | NCT03086148 |
|---|---|
| Other IDs: | 3/16/17 |
| Study URL: | https://ClinicalTrials.gov/show/NCT03086148 |
Last updated: Jun 17, 2022