Ketamine for Depression: An MRI Study

Brief Summary

Ketamine has been shown to decrease symptoms of anxious depression quickly. This decrease has been shown to last for up to one month. MRI technology will be used before and after ketamine for patients with depression to examine the extent to which certain brain areas predict ketamine's antidepressant effects.

Intervention / Treatment

  • Drug: Ketamine
  • Other: Magnetic Resonance Imaging (MRI)

Condition or Disease

  • Depression
  • Anxious Depression
  • Major Depressive Disorder

Phase

Study Design

Study type: Interventional
Status: Completed
Study results: Has Results
Age: 18 Years to 64 Years   (Adult)
Enrollment: 25 ()
Funded by: Other|NIH

Masking

Clinical Trial Dates

Start date: Mar 16, 2022
Primary Completion: Dec 29, 2017
Completion Date: Dec 29, 2017
Study First Posted: Sep 09, 2015
Results First Posted: Apr 04, 2019
Last Updated: Apr 16, 2019

Sponsors / Collaborators

Lead Sponsor: N/A
Responsible Party: N/A

Ketamine's antidepressant effects were measured with Hamilton Depression Rating Scale (HDRS). MRI data will also be analyzed to examine the extent to which certain brain areas predict ketamine's antidepressant effects.

Eligibility Criteria

Sex: All
Minimum Age: 18
Maximum Age: 64

More Details

NCT Number: NCT02544607
Other IDs: 2015P001912|24032
Study URL: https://ClinicalTrials.gov/show/NCT02544607
Last updated: Jun 17, 2022