Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine
Brief Summary
The purpose of this study is the determination of blood concentration and the effectiveness of esketamine after nasal application.
Study Design
| Study type: | INTERVENTIONAL |
|---|---|
| Status: | Completed |
| Study results: | No Results Available |
| Age: | 18 Years to 45 Years |
| Funded by: | Other |
Masking |
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Clinical Trial Dates
| Start date: | Feb 01, 2009 | |
|---|---|---|
| Primary Completion: | Aug 31, 2020 | |
| Completion Date: | Oct 01, 2009 | ACTUAL |
| Study First Posted: | Feb 19, 2009 | ESTIMATED |
| Results First Posted: | Aug 31, 2020 | |
| Last Updated: | Dec 01, 2010 |
Sponsors / Collaborators
Lead Sponsor:
N/A
Responsible Party:
N/A
Location
Eligibility Criteria
| Sex: | Male |
|---|---|
| Minimum Age: | 18 |
| Maximum Age: | 45 |
| Healthy Volunteers: | Yes |
Inclusion Criteria:
* male
* age ≥18 years ≤ 45 years
* healthy
* non-smoking
* BMI 18-27
Exclusion Criteria:
* abuse of drugs
* known or supposed hypersensitivity and/or contraindication against ketamine or additives
* participation of another clinical study within the last 30 days
* chronic obstructed nose breathing or nasal polyps
* dug allergy
* blood donation within the last two months
* male
* age ≥18 years ≤ 45 years
* healthy
* non-smoking
* BMI 18-27
Exclusion Criteria:
* abuse of drugs
* known or supposed hypersensitivity and/or contraindication against ketamine or additives
* participation of another clinical study within the last 30 days
* chronic obstructed nose breathing or nasal polyps
* dug allergy
* blood donation within the last two months
More Details
| NCT Number: | NCT00847418 |
|---|---|
| Other IDs: | EKBB 351/08, 2009DR1015 |
| Study URL: | https://clinicaltrials.gov/study/NCT00847418 |
Last updated: Sep 29, 2023